COX1 — Candida albicans

Summary

CM_00220W (COX1) on the Candida albicans mitochondrial chromosome encodes a protein with cytochrome-c oxidase activity, endonuclease activity, heme binding, and hydrolase activity, belonging to the Cyt_c_oxase-like_su1 domain family and containing a homing endonuclease domain. It is associated with aerobic respiration, oxidative phosphorylation, electron transport coupled proton transport, mitochondrial electron transport from cytochrome c to oxygen, intron homing, mitochondrial transcription, RNA breakdown, prostaglandin and fatty acid anabolism, and secretion. The protein localizes to the mitochondrial inner membrane, respiratory chain complex IV, and membrane. Studies of related genes in other species link the family to cytochrome-c oxidase (EC 7.1.1.9) and hydrolase (EC 3.1.-.-) activities.