LIP9 — Candida albicans

Summary

C7_02880C_A (LIP9, also known as CaTRI8 or TRI8) on Candida albicans chromosome 7 encodes a secreted lipase belonging to the lipase_secreted and AB_hydrolase families, with confirmed lipase and triacylglycerol lipase (EC 3.1.1.3) activity. This gene is associated with lipolysis, biofilm formation, hyphal growth, filamentous growth in response to starvation and biotic stimuli, germ tube formation, host invasion, secretion, sensitization, cell death, and ergosterol anabolism. The encoded protein localizes extracellularly. Related genes in other species, including Fusarium oxysporum, are linked to secreted lipolytic activity, though these associations are not yet established for LIP9 itself.