zrcA — Aspergillus fumigatus

Summary

AFU7G06570 (symbol zrcA) on chromosome 7 of Aspergillus fumigatus encodes a cation diffusion facilitator family metal ion transporter. The product possesses zinc ion transmembrane transporter and zinc ion sequestering activities and is associated with detoxification of zinc ions, cellular zinc ion homeostasis, zinc import into the endoplasmic reticulum, and general zinc ion membrane transport. It has been linked to nitric oxide storage, detoxification, and hypersensitivity. The protein localises to the nuclear membrane, fungal-type vacuole membrane, ER membrane, and membrane.