cdpNPT — Aspergillus fumigatus

Summary

AFU8G00620 (symbol cdpNPT) on Aspergillus fumigatus chromosome 8 encodes a protein with tryptophan dimethylallyltransferase activity, prenyltransferase activity, and aminopeptidase activity, placing it in the DMATS-type fungal prenyltransferase family. The gene is associated with alkaloid biosynthesis, including ergot and indole alkaloid anabolism, as well as prenylation and proteolysis. Studies of related genes in other species, such as dmaW and cpd1, link the family to tryptophan prenylation and alkaloid production.