Arp1 — Aspergillus fumigatus

Summary

AFU8G01360 (Arp1) on chromosome 8 of Aspergillus fumigatus encodes an amidase domain-containing protein with lyase activity. This gene is associated with DHN-melanin biosynthesis, pigmentation, melanin anabolism, and sporulation. It is also linked to L-phenylalanine breakdown and immune evasion. Studies of related genes in other species connect the family to lyase activity (EC 4.2.1.-), though this specific activity is not yet established for Arp1 itself.