ftmG — Aspergillus fumigatus

Summary

AFU8G00240 (ftmG) on Aspergillus fumigatus chromosome 8 encodes a cytochrome P450 monooxygenase (EC 1.14.14.119) with heme and iron binding, acting on paired donors with incorporation of molecular oxygen. This membrane-localised enzyme is associated with secondary metabolism, specifically verruculogen anabolism, as well as alkaloid and terpenoid anabolism. Related genes in other species link the family to diverse oxidoreductase activities, though these specific functions are not established for ftmG itself.