ssp1 — Schizosaccharomyces pombe 972h-

Summary

SPCC297.03 (ssp1, also known as SpSTK-22) on chromosome 3 of Schizosaccharomyces pombe encodes a serine/threonine protein kinase with calcium/calmodulin-dependent and protein kinase A activities, calmodulin and phospholipid binding, and ATP binding. The gene is associated with glucose and energy homeostasis, the CAMKK-AMPK signaling cascade, actin depolymerization, microtubule dynamics, negative regulation of cytoplasmic translation and inositol phosphate biosynthesis, mycose catabolism, regulation of invasive growth in response to glucose limitation, upregulation of gluconeogenesis, positive and negative regulation of pseudohyphal growth, single-species surface biofilm formation, fungal-type cell wall assembly, septin ring assembly, and cell cycle switching from mitotic to meiotic. The product localizes to the nucleotide-activated protein kinase complex, septin rings, cell cortex of growing cell tips, cellular bud neck, mitotic spindle pole body, nuclear membrane, and perinuclear space.