ccq1 — Schizosaccharomyces pombe 972h-
Summary
SPCC188.07, also known as ccq1, encodes a protein that localizes to the telomere cap complex, subtelomeric heterochromatin, and the chromosome telomeric repeat region in Schizosaccharomyces pombe 972h- on chromosome 3. The product possesses bridging binding activity and is associated with telomere-telomerase complex assembly, meiotic telomere clustering, telomere maintenance via telomerase, telomere capping, and chromatin silencing. It is linked to meiotic chromosome segregation, prophase, metaphase, anaphase, cell cycle modulation, DNA damage checkpoint, homology-directed repair, and post-transcriptional gene silencing. The gene is also connected to telomeric silencing. Related genes in other species indicate the protein is part of the telosome complex.
Annotations
- Chromosome
- 3
- GO terms
- Cell Cycle, Anaphase, Metaphase, S Phase, Prophase, PTGS, Cell Death, Nucleus
- Publications
- PMID:21333630, PMID:17289569, PMID:18535244, PMID:15546621, PMID:27264871, PMID:19141478, PMID:27253066, PMID:25131669