ADH1 — Schizosaccharomyces pombe 972h-

Summary

SPCC13B11.01 (ADH1) on chromosome 3 of Schizosaccharomyces pombe encodes an alcohol dehydrogenase (ADH) with ethanol dehydrogenase (NAD+) activity (EC 1.1.1.1), also possessing aldo-keto reductase (NAD) activity and zinc binding. The protein contains ADH-like and GroES-like domains. ADH1 is associated with ethanol fermentation, malolactic fermentation, malate transport, and fermentation broadly. It is linked to sporulation, meiosis, mating, pheromone response, cell differentiation, and gene conversion. The gene has been connected to homologous recombination, DNA repair, regulation of gene expression, secretion, and regeneration. It is also associated with response to zinc and homeostasis. The protein localises to the cytoplasm, mitochondrial lumen, and fungal biofilm matrix.