sap1 — Schizosaccharomyces pombe 972h-

Summary

SPCC1672.02C (sap1) on chromosome 3 of Schizosaccharomyces pombe 972h- encodes a sequence-specific double-stranded DNA-binding protein belonging to the Sap1_N family. The protein is localised to chromatin and the nucleus. Sap1 is associated with site-specific DNA replication termination, replication fork arrest at rDNA repeats, and mitotic pre-replicative complex assembly. It is also linked to cell fate determination, centromere separation, DNA condensation, gene conversion at the mating-type locus, transposition, mating type switching, phenotypic switching, G1 phase, chromatin silencing, regulation of gene expression, DNA anabolism, DNA recombination, chromatin organization, and cytokinesis.