ten1 — Schizosaccharomyces pombe 972h-

Summary

SPCC1393.14 (ten1) on chromosome 3 of Schizosaccharomyces pombe 972h- encodes the Ten1 protein, a member of the Ten1_fungal family with an OB-fold nucleic-acid-binding domain. The product binds telomeric single-stranded DNA and is a component of the telomere cap complex, localizing to chromosome telomeric repeat and telomeric regions. The gene is associated with telomere localization, capping, and maintenance, as well as DNA replication, repair, homologous recombination, sumoylation, cell cycle modulation, and homeostasis. Related genes in other species link the family to the CST complex.