cdc14 — Schizosaccharomyces pombe 972h-

Summary

SPBC24C6.07 (cdc14) in Schizosaccharomyces pombe 972h- on chromosome 2 encodes a protein with a Cell_div_Cdc14 domain and ARM-type fold, and has protein kinase activator activity. The gene is associated with numerous mitotic processes, including spindle midzone assembly, spindle elongation, spindle breakdown, spindle checkpoint, chromosome biorientation, and regulation of mitosis. It is also linked to mitotic prometaphase, prophase, telophase, interphase, M phase, and the septation initiation network (SIN) regulating cytokinesis. Additional associations include ciliogenesis, cell fate determination, spore germination, and protein dephosphorylation. The product localises to the new spindle pole body (SPB).