pho7 — Schizosaccharomyces pombe 972h-

Summary

SPBC27B12.11C (pho7) on chromosome 2 of Schizosaccharomyces pombe encodes an uncharacterized transcriptional regulatory protein that contains a Zn2-C6 fungal-type DNA-binding domain and is annotated with sequence-specific DNA-binding transcription activator activity for RNA polymerase II. The gene is associated with cellular response to phosphate starvation, intracellular Pi homeostasis, and the glucose effect, as well as broader responses to nutrient and starvation conditions. It is linked to lncRNA transcription, ribosome biogenesis, autophagy, signal transduction, chromatin remodeling, and positive regulation of transcription by RNA polymerase II. The encoded protein localizes to the nucleus, chromatin, and cytosol.