sid4 — Schizosaccharomyces pombe 972h-

Summary

SPBC244.01C (sid4) on chromosome 2 of Schizosaccharomyces pombe 972h- encodes a Sid4-like protein with signaling adaptor activity. The gene product is associated with the mitotic spindle checkpoint, cytokinesis, and the septation initiation network (SIN), including downregulation of both cytokinesis and septation initiation signaling. It is linked to spindle assembly, microtubule nucleation, membrane assembly, and nuclear division, as well as progression through interphase, metaphase, anaphase, meiosis I, and meiosis II. Localization evidence connects Sid4 to the mitotic and meiotic spindle pole bodies, including the outer plaque of the mitotic spindle pole body and the meiotic spindle pole.