mbx1 — Schizosaccharomyces pombe 972h-

Summary

SPBC19G7.06 (symbol mbx1) on chromosome 2 of Schizosaccharomyces pombe 972h- encodes a MADS-box transcription factor of the SRF-like family, possessing DNA-binding transcription activator activity specific to RNA polymerase II and protein dimerization activity. The gene is associated with cell cycle regulation, including G1 and G2 phases, cytokinesis, and cell division, as well as signal transduction, hypersensitivity, and positive regulation of transcription by RNA polymerase II. It is linked to gene expression regulation and homeostasis, with the product localizing to the cytosol. Related genes in other species connect the family to the M/G1 phase-specific MADS box-forkhead transcription factor complex.

Annotations

Chromosome
2
GO terms
Cell Cycle, Hypersensitivity, Cytokinesis, G2 Phase, G1 Phase, DNA-binding Transcription Factor Activity, RNA Polymerase II-specific, DNA-dependent transcription, Positive Regulation Of Transcription By RNA Polymerase II
Publications
PMID:15509866, PMID:18057023, PMID:20032302, PMID:26237280, PMID:21804323