SOD2 — Schizosaccharomyces pombe 972h-

Summary

SpSOD2 (SPAC1486.01) on chromosome 1 of Schizosaccharomyces pombe encodes a manganese/iron superoxide dismutase (EC 1.15.1.1) with superoxide dismutase activity, manganese binding and IgE binding functions. The protein localises to mitochondria and cytosol. SpSOD2 is associated with removal of O2-, detoxification, oxidative phosphorylation, apoptotic process, cell cycle modulation, DNA damage checkpoint, MAPK cascade, and regulation of K+ transport and sodium transport. It is linked to seed germination, digestion, mitochondrial translation, and evasion or tolerance of host-produced AOS. Trait associations include photosynthetic rate, sodium concentration, and salt tolerance. Phenotypic connections include altered fermentative and respiratory metabolism, increased freeze-thaw and hydrostatic pressure resistance, decreased radiation resistance, abnormal spore wall and septum formation, and changes in cell cycle progression, stationary phase entry, and meiotic recombination.