moa1 — Schizosaccharomyces pombe 972h-

Summary

SPAC15E1.07C (moa1) in Schizosaccharomyces pombe 972h- on chromosome 1 encodes a protein with kinetochore adaptor activity. The gene is associated with numerous meiotic processes, including homologous chromosome segregation, meiotic chromosome segregation, meiosis I and II, second meiotic division, regulation of monopolar attachment, homologous chromosome orientation in meiotic metaphase I, spindle attachment to meiosis I kinetochore, anaphase cohesion protection, and karyogamy. It is also linked to mitotic chromosome segregation, DNA replication checkpoint, mRNA 3'-end processing, protein positioning, centromere localization, and meiotic S phase. The product localizes to the kinetochore, CENP-A containing chromatin, and the nucleus.