SWI6 — Saccharomyces cerevisiae S288c

Summary

YLR182W in Saccharomyces cerevisiae S288c encodes a DNA-binding transcription regulator with both repressor and activator activities specific to RNA polymerase II, and it also possesses transcription coactivator activity and promoter-specific chromatin binding. The protein is a component of the SBF and MBF complexes and localises to chromatin, the cytoplasm, cytosol and nucleus. YLR182W is associated with cell cycle transitions, including G1 phase and M phase, cell cycle checkpoints, cell size control, response to nutrients, ethanol fermentation, sphingolipid metabolism, cell wall biogenesis, nucleocytoplasmic transport, and response to MMS. Traits linked to this gene include zinc sensitivity, turgor pressure, potassium concentration, oxidative stress, and acid sensitivity. Phenotypes connected to YLR182W involve altered cell size, cell shape, cell cycle progression, fermentative metabolism, respiratory growth, thermotolerance, oxidative stress resistance, and toxin resistance.