BMH1 — Saccharomyces cerevisiae S288c

Summary

YER177W in Saccharomyces cerevisiae S288c encodes a 14-3-3 family protein with protein sequestering activity. This gene is associated with diverse biological processes including TOR signaling, exocytosis, stress response, carbohydrate metabolism, regulation of proteolysis, double-strand break repair, dephosphorylation, secretion regulation, nuclear export, glucose homeostasis, stringent response, mitotic cytokinesis checkpoint, and DNA repair upregulation. It localizes to the actomyosin contractile ring, yeast-form cell wall, mitotic spindle midzone, telomeric region, extracellular vesicles, spindle pole body, cell tip, and division site. YER177W is linked to traits including potassium uptake and concentration, salt tolerance, and oxidative stress. Phenotypic associations include increased viability, desiccation resistance, and apoptosis, as well as altered thermotolerance, replicative lifespan, carbon and nitrogen source utilization, invasive growth, metal resistance, and osmotic stress resistance.