SLI15 — Saccharomyces cerevisiae S288c

Summary

YBR156C encodes a protein that contains an inner centromere protein ARK-binding domain. The gene is associated with chromosome biorientation, spindle elongation, the spindle assembly checkpoint, metaphase, response to nocodazole, spindle assembly, spindle midzone assembly, carbohydrate utilization, cell cycle control, sister chromatid cohesion, cytokinesis, anaphase, chromosome division, S phase, ribosome biogenesis, mitosis, sporulation, and centromere localization. Phenotypic associations include decreased chromosome segregation, abnormal budding, increased telomere length, abnormal vegetative growth, abnormal cell cycle progression, abnormal chromosome/plasmid maintenance, increased innate thermotolerance, decreased endocytosis, increased invasive growth, increased metal resistance, decreased UV resistance, decreased chromosome/plasmid maintenance, decreased stress resistance, abnormal protein/peptide distribution, decreased vegetative growth, decreased metal resistance, increased heat sensitivity, haploinsufficiency, decreased vegetative growth rate, decreased competitive fitness, increased resistance to chemicals, viability, and decreased resistance to chemicals. The gene is also linked to acid sensitivity and oxidative stress traits.