AZR1 — Magnaporthe oryzae 70-15

Summary

MGG_00166 (MoAZR1, also known as MoPPMA or MoPTC7) on chromosome 5 of Magnaporthe oryzae 70-15 encodes a protein serine/threonine phosphatase (EC 3.1.3.16) belonging to the PPTC7 and PPM-type phosphatase-like domain families, with metal-binding activity. The gene is associated with dephosphorylation, protein phosphorylation, signal transduction, and upregulation of ubiquinone anabolism, and its product localises to mitochondria. MoAZR1 has been connected to interactions with barley (Hordeum vulgare) and rice (Oryza sativa), and to the rice blast disease. Studies of related genes in other species link the family to protein phosphatase activity and mitochondrial carrier domains, though these associations are not established for MoAZR1 itself.