ABCA — Magnaporthe oryzae 70-15

Summary

MoABCA (MGG_00447) on chromosome 5 of Magnaporthe oryzae 70-15 encodes a protein with ABCG_PDR_1, ABCG_PDR_2, and other ABC transporter domains, and is annotated with ATP-coupled transmembrane transporter activity, ABC transporter activity, ATP hydrolase activity, and ATP binding. The gene is associated with ATP-coupled transmembrane transport, xenobiotic detoxification via export across the plasma membrane, and localisation to the plasmalemma. It is also associated with appressorium formation, response to antibiotics, stimulus detection, protein dephosphorylation, cell death, hypersensitivity, and DNA repair. Phenotypic associations include altered small molecule transport, increased sporulation, decreased cell death rate, delayed mitophagy, abnormal replicative and chronological lifespan, and defects in nutrient uptake, cell fusion, endocytosis, pseudohyphal growth, and cell cycle progression. Sequence similarity links related genes in other species to plant height, root length, drought tolerance, and oxidative stress response, and to unaffected pathogenicity.