CAG1 — Magnaporthe oryzae 70-15

Summary

MGG_00365 (CAG1, also known as MAGB) encodes a fungal G-protein alpha subunit that binds GTP. In Magnaporthe oryzae, this gene is associated with appressorium formation, host invasion, thigmotropism, asexual and sexual reproduction, conidiation, autolysis, programmed cell death, and regulation of secondary metabolite biosynthesis including sterigmatocystin and penicillin. It localises to the heterotrimeric G-protein complex, cytoplasm, and mitochondrial outer membrane. The gene is linked to rice blast disease. Studies of related genes in other species connect the family to loss of pathogenicity, mating efficiency, pheromone response, cell cycle progression, and pseudohyphal growth, as well as traits such as germination rate and protein content.