FHL1 — Magnaporthe oryzae 70-15

Summary

MGG_00170 (FHL1, also known as MoFHL1, MoPTS1, MoPRE2) on chromosome 5 of Magnaporthe oryzae 70-15 encodes a proteasome subunit beta with threonine endopeptidase activity (EC 3.4.25.1). The gene is associated with 20S proteasome assembly, ubiquitin-independent protein catabolism, response to nutrient levels, morphogenesis, and lipid metabolism. Its product localizes to the proteasome core complex, peroxisome, nuclear envelope, cytoplasm, cytosol, and nucleus. FHL1 is linked to turgor pressure, cell cycle progression (including G2/M phase transition and M phase), UV resistance, transposable element transposition, mutation frequency, polyploidy, pheromone sensitivity, shmoo formation, survival in stationary phase, protein secretion, mitochondrial rho- mutation frequency, axial budding pattern, mating response, silencing, respiratory metabolism, and Golgi morphology. Studies of related genes in other species connect the family to proteasome function and protein content.