PEX13 — Magnaporthe oryzae 70-15

Summary

MGG_00157 (MoPEX13) on chromosome 5 of Magnaporthe oryzae 70-15 encodes a peroxin-13 family protein containing an N-terminal Peroxin-13 domain and an SH3 domain. The gene product is associated with the peroxisomal import pore and peroxisome membrane, and is linked to biological processes including peroxisomal matrix protein import, protein-peroxisome targeting, sexual reproduction, and morphogenesis. Associations with numerous phenotypes have been observed, including absent peroxisomal transport and morphology, absent spore germination, delayed meiosis and autophagy, abnormal vegetative growth and sporulation, decreased chitin deposition, and increased respiratory growth rate. Studies of related genes in other species link the PEX13 family to acid sensitivity and oxidative stress response.