ABC2 — Magnaporthe oryzae 70-15

Summary

MGG_00141 (MoABC2) on chromosome 5 of Magnaporthe oryzae 70-15 encodes an ABC-type transporter with ATP hydrolase activity, belonging to the type 1 exporter family and containing ABC transporter-like ATP-binding domains. The gene is associated with xenobiotic detoxification via transmembrane export across the plasma membrane, oligopeptide export from the mitochondrion, and response to antibiotics. It is linked to host invasion, invasive growth, morphogenesis, cell wall biogenesis, autophagy, secondary metabolism, and signal transduction. Localisation evidence connects the product to the fungal-type vacuole, mitochondrial inner membrane, and plasmalemma. Phenotypic associations include altered vacuolar morphology and distribution, decreased endocytosis, abnormal cell cycle progression, increased entry into G0 stationary phase, and absent resistance to oxidative and hyperosmotic stress.