EXO84 — Fusarium odoratissimum str. race 4

Summary

FoEXO84 (FOC4_G10011589) from Fusarium odoratissimum str. race 4 encodes a protein containing Exo84_C and PH-like domains, placing it in the exocyst complex subunit family. The gene is associated with exocyst assembly and localization, exocytosis, Golgi-to-plasma membrane transport, protein secretion, and spliceosomal complex assembly. It localizes to the exocyst, transport vesicles, and cellular bud sites. Phenotypic associations link FoEXO84 to abnormal sporulation efficiency, filamentous growth, budding, septum formation, chitin deposition, and spore wall formation, as well as decreased intracellular transport, delayed protein transport, and increased mating efficiency. The gene is also associated with altered cell cycle progression, including increased duration and premature metaphase/telophase progression, and with decreased pexophagy and shmoo formation. Related genes in other species, such as SRO7 and CDC42, further connect the exocyst family to polarized secretion and cell morphogenesis.