CUT9 — Fusarium odoratissimum str. race 4

Summary

FoCUT9 (CUT9, CDC16) on chromosome KB726554 of Fusarium odoratissimum str. race 4 encodes a tetratricopeptide repeat (TPR)-containing protein with enzyme-substrate adaptor activity. It is associated with the anaphase-promoting complex-dependent catabolic process, protein ubiquitination, regulation of protein secretion, cell division, and activation of mitotic sister chromatid resolution. The product localizes to the cyclosome, cytoplasm, cytosol, and centric heterochromatin. Phenotypic associations link the gene to cell cycle arrest at multiple phases (G1/S, G2, metaphase/anaphase, telophase), absent chromosome segregation and meiotic recombination, premature or arrested meiosis, decreased flocculation and adhesion, absent spore wall formation, and absent UV resistance. The gene is also connected to differential expression under temperature and salt stress conditions in the Fusarium oxysporum f. sp. cubense TR4 lineage.