BUB2 — Fusarium odoratissimum str. race 4

Summary

FoBUB2 (FOC4_G10015240) in Fusarium odoratissimum str. race 4 encodes a protein containing a Rab-GAP TBC domain, placing it in the Rab-GAP_TBC_sf family. The gene is associated with negative regulation of division septum assembly, regulation of protein secretion, and downregulation of mitotic cytokinesis and septation initiation signaling. It localizes to the SIN/MEN two-component GAP complex, spindle pole bodies, cytosol, and nucleus. Phenotypic associations include abnormal cell cycle progression, premature metaphase-anaphase transition, increased sporulation, decreased flocculation, and altered mating efficiency. The gene is also linked to responses to Congo Red, NaCl, and temperature stress. Studies of related genes in other species connect the family to cell cycle control and septation.