HEX1 — Fusarium graminearum PH-1

Summary

FgHEX1 (FGRAMPH1_01G03177) on chromosome 1 of Fusarium graminearum PH-1 encodes a beta-hexosaminidase, an enzyme with beta-N-acetylglucosaminidase and hexosaminidase activity that belongs to the glycoside hydrolase superfamily. The gene is associated with chitobiose catabolism, polysaccharide breakdown, and broader carbohydrate metabolism. It is linked to asexual reproduction, hyphal growth, defense responses, and antiviral responses. The encoded protein is localized to the membrane and extracellular space. Studies of related genes in other species link the family to reduced virulence and protein content traits, though these associations are not yet established for FgHEX1 itself.