AOX — Fusarium graminearum PH-1

Summary

FgAOX (FGRAMPH1_01G03311) on chromosome 1 of Fusarium graminearum PH-1 encodes a member of the alternative oxidase superfamily, with annotated alternative oxidase activity and metal binding. The protein is localised to the mitochondrial inner membrane and mitochondria. FgAOX is associated with alternative respiration, the electron transport chain, ATP anabolism, the TCA cycle, gluconeogenesis, lipid metabolism, programmed cell death, hypersensitivity, and cell death. It has also been connected to mycotoxin anabolism, secondary metabolite biosynthesis, homeostasis, and oxidative stress response. Related genes in other species, including Fusarium oxysporum and Verticillium dahliae, are linked by sequence similarity.