MYO1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G03465 (MYO1) in Fusarium graminearum PH-1 encodes a myosin-I family protein with microfilament motor activity, F-actin binding, and ATP binding. It localizes to the actin cytoskeleton, hyphal tip, and cell tip. MYO1 is associated with actin filament organization, actin polymerization and depolymerization, endocytosis, receptor-mediated endocytosis, hyphal growth, sexual reproduction, and response to mycotoxin. It is also linked to mycotoxin anabolism and hypersensitivity. Phenotypic associations include abnormal filamentous growth, absent spore germination, sterility, decreased endocytosis rate, delayed cytokinesis, and abnormal prion inheritance. Studies of related genes in other species link the family to virulence and pathogenicity, though this has not been established for MYO1 itself.