CDC11 — Fusarium graminearum PH-1

Summary

FgCDC11 (FGRAMPH1_01G04015) on chromosome 1 of Fusarium graminearum PH-1 encodes a protein with a CDIRP family signature. The product possesses protein phosphatase activator, protein phosphatase regulator, and signaling adaptor activities. It is associated with the septation initiation network (SIN) and the PTW/PP1 phosphatase complex, localizing to the mitotic and meiotic spindle pole bodies, the SIN/MEN signaling complex, cytoplasm, cytosol, and nucleus. The gene is linked to mitotic cytokinesis regulation, activation of mitotic sister chromatid resolution and division septum assembly, upregulation of the metaphase/anaphase transition, mitotic exit, cell morphogenesis, nuclear division, hyphal growth, and cell cycle progression. Studies of related genes in other species connect the family to protein content traits.