FSL3 — Fusarium graminearum PH-1

Summary

FSL3 (FGRAMPH1_01G04425) on chromosome 1 of Fusarium graminearum PH-1 encodes a protein with galactose mutarotase-like and aldose 1-epimerase domains, and has been annotated with UDP-glucose 4-epimerase and aldose 1-epimerase activities, as well as sugar binding. The gene is associated with monosaccharide metabolism, the Leloir pathway, and UDP-galactose, galactose, and glucose metabolism. Its product is predicted to localize to the cytosol and extracellular space. Studies of related genes in other species link the family to aldose 1-epimerase function and apoplastic effector activity, though these roles are not established for FSL3 itself.