CHS7 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G04739 (CHS7, also known as FgCSMB) in Fusarium graminearum PH-1 on chromosome 1 encodes a protein with chitin synthase activity and cytoskeletal motor activity, and it binds actin and ATP. The product contains domains including a chitin synthase domain, a myosin head motor domain, and a kinesin motor domain. CHS7 is associated with cell wall biogenesis, chitin anabolism, fungal-type cell wall organization, and homologous recombination. It localizes to the myosin complex, cytoplasmic vesicle membrane, cross wall, cell periphery, cell tip, and plasmalemma. Related genes in other species are linked to loss of pathogenicity and reduced virulence.