HEX1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G01363 (HEX1) on chromosome 1 of Fusarium graminearum PH-1 encodes a beta-hexosaminidase, a member of the glycoside hydrolase family 20. The enzyme exhibits beta-N-acetylglucosaminidase and beta-N-acetylhexosaminidase activities. The gene is associated with the chitobiose catabolic process, glycosaminoglycan metabolism, and polysaccharide breakdown, as well as with asexual reproduction and hyphal growth. The encoded protein is linked to the extracellular and membrane. Studies of related genes in other species connect the HEX1 family to reduced virulence, though this has not been established in F. graminearum.