ABC2 — Fusarium graminearum PH-1

Summary

FgABC2 (FGRAMPH1_01G01381) on chromosome 1 of Fusarium graminearum PH-1 encodes an ABC-type oligopeptide transporter with ATP hydrolase activity and ATP-coupled transmembrane transporter activity. The protein belongs to the type 1 exporter family and is localized to the mitochondrial inner membrane, plasma membrane, and general membrane. It is associated with oligopeptide export from mitochondria, sterol anabolism, secretion, membrane transport, and homeostasis. Phenotypic associations link the gene to absent oxidative and hyperosmotic stress resistance, decreased hypoosmotic stress resistance, abnormal cell cycle progression, increased pexophagy, decreased endocytosis, and abnormal vacuolar and peroxisomal distribution. The gene is also connected to changes in colony color, protein/peptide accumulation rates, and entry into G0 stationary phase. Studies of related genes in other species link the family to leaf width and leaf shape traits and oxidative stress response.