AMT1 — Fusarium graminearum PH-1

Summary

FgAMT1 (FGRAMPH1_01G01573) on chromosome 1 of Fusarium graminearum PH-1 encodes a protein with ammonium channel and methylammonium transmembrane transporter activities, and contains ammonium transporter domains. The gene is associated with ammonium and methylammonium membrane transport, nitrate metabolism, and ammonium import across the plasma membrane. It is also linked to sexual reproduction, hyphal growth, nuclear export, and methylation. The product localizes to the plasma membrane, fungal-type vacuole, and Golgi complex. Phenotypic associations include increased virulence and sporulation, abnormal biofilm formation, flocculation absence, altered cell cycle progression, decreased nitrogen source utilization, abnormal autophagy and pexophagy, increased necrotic cell death, and abnormal respiratory metabolism. Related genes in other species link the family to nitrogen utilization.