MIH1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G01439 (MIH1, also known as FgNIMT or FgCDC25) in Fusarium graminearum PH-1 encodes a protein with a MPI_Phosphatase domain and a Rhodanese-like domain, and has been annotated with protein tyrosine phosphatase activity and protein phosphatase activity. The gene is associated with positive regulation of the G2/MI transition of the meiotic cell cycle, upregulation of mitosis, response to mitotic G2 DNA damage checkpoint signaling, G2 cell size control checkpoint, regulation of cell cycle switching from mitotic to meiotic, intra-S DNA damage checkpoint, sexual reproduction, mitotic G2/M transition, positive regulation of mitotic entry, and cell division. Its product localises to the cytoplasm, cytosol, and nucleus. Studies of related genes in other species link the family to M-phase inducer phosphatase function (EC 3.1.3.48) and, more distantly, to traits such as root width, cell membrane stability, leaf shape, and protein content.