AMT1 — Fusarium graminearum PH-1

Summary

FgAMT1 (AMT1) on chromosome 1 of Fusarium graminearum PH-1 encodes an ammonium transporter/urea transporter family protein with ammonium channel and methylammonium transmembrane transporter activities. The gene is associated with ammonium and methylammonium membrane transport, nitrate metabolism, sexual reproduction, hyphal growth, nuclear export, and methylation. The product localises to the plasma membrane, fungal-type vacuole, and Golgi complex. Phenotypic associations link FgAMT1 to abnormal biofilm formation, flocculation, and filamentous growth; increased virulence, sporulation, and necrotic cell death; altered cell cycle progression; decreased nitrogen source utilisation; and abnormal autophagy, pexophagy, and respiratory metabolism. Related genes in other species link the ammonium transporter family to protein and phosphate content traits.