LSM2 — Fusarium graminearum PH-1

Summary

FgLSM2 (FGRAMPH1_01G00951) on chromosome 1 of Fusarium graminearum PH-1 encodes a protein with an Sm domain and U6_snRNA_Lsm2 family signature, and is annotated for U2 snRNA and RNA binding. The gene is associated with RNA splicing, processing, folding, and surveillance, as well as telomerase holoenzyme complex assembly, sexual reproduction, and mycotoxin anabolism. Its product localizes to spliceosomal complexes, U6 and U2 snRNPs, P bodies, and the nucleolus. Phenotypically, FgLSM2 is linked to decreased spore germination, mating response, and invasive growth, abnormal cytokinesis and cell cycle progression, increased apoptosis, and altered fermentative and respiratory metabolism.