FAS2 — Candida albicans
Summary
C3_04830C_A (FAS2, also known as CaFAS2, CaCEL-1, CEL-1) in Candida albicans encodes a protein with domains characteristic of the fungal fatty acid synthase alpha subunit, including FASI_helical, FAS_alpha_yeast, Fas_alpha_ACP, FAS_alpha_su_C, Ppantetheine-prot_Trfase_dom, ACPS, Fungal_FAS, 4-PPantetheinyl_Trfase_dom, 4-PPantetheinyl_Trfase_dom_sf, Ketoacyl_synth_AS, Ketoacyl_synth_C, PKS_Beta-ketoAc_synthase_dom, Ketoacyl_synth_N, Thiolase-like, PP-bd_ACP, and Acyl_Trfase/lysoPLipase. It is annotated with fatty-acyl-CoA synthase activity, 3-oxoacyl-ACP reductase activity, ketoacyl-ACP synthase activity, phosphopantetheinyltransferase activity, fatty acid synthase activity, pigment binding, and Mg binding. The gene is associated with palmitic acid biosynthetic process, lipid A anabolism, long-chain fatty acid anabolism, adiposome formation, mitotic nuclear membrane biogenesis, response to glucose, immune response, disruption of host phagocytosis, response to heat, electron transport chain, DNA anabolism, single-species biofilm formation on in
Annotations
- Chromosome
- 3
- Related genes
- FAS2, UTP10, BMH2, UBR1, SET4, SUP35, ATG8, MID1
- GO terms
- Immune Response, Biofilm Formation, Cell Death, Cytosol, Electron Transport Chain, Fatty Acid Synthase Activity, fatty acid anabolism, ketoacyl-ACP synthase activity
- Publications
- 19214209, 34849884, 19299562, 9891066, 22543816, 9482897, 28379007, 28614721
- Traits
- RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, STRESS RESISTANCE: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, NUCLEAR POSITION: ABNORMAL, RNA ACCUMULATION: INCREASED, SPORULATION EFFICIENCY: DECREASED