CAT1 — Candida albicans

Summary

CAT1 (also known as GAP2, PER1, and other synonyms) on Candida albicans chromosome 3 encodes an amino acid permease belonging to the APC/YAT family, with L-arginine and L-lysine transporter activity. The gene is associated with amino acid import, nitrogen utilization, nitrogen catabolite repression, and SAM transport, as well as with regulation of growth, germ tube formation, tube formation, cell-cell signaling, circadian rhythm, wound healing, response to glutathione, response to iron, oxidative stress response, phospholipid transport, glycan biosynthesis, and metabolic burst. It localizes to the plasma membrane, cell tip, cell division site, Golgi membrane, fungal-type cell wall, extracellular vesicle, and medial membrane band. Phenotypic associations include altered nutrient uptake, cell cycle progression, adhesion, sporulation, endocytosis, replicative lifespan, and hydrostatic pressure resistance. Related genes in other species link the family to .