RAS2 — Candida albicans

Summary

C3_04480C_A (RAS2) on Candida albicans chromosome 3 encodes a small GTPase of the Ras-type family, possessing GTPase activity, GTP binding, and G protein activity. This gene is associated with Ras protein signal transduction, cAMP anabolism, and prenylation. It is linked to biofilm formation, sexual reproduction, pheromone response, response to glucose, and cell physiology. Additional associations include membrane addition at the site of cytokinesis, ascospore-type prospore assembly, establishment or maintenance of cell polarity, exocytosis, vesicle fusion, Golgi to plasma membrane transport, aerobic respiration, the TCA cycle, sterol metabolism, and GPI anchor anabolism. The product localizes to the plasma membrane, transport vesicle membrane, incipient cellular bud site, mating projection tip, and fungal biofilm matrix. Related genes in other species link the family to the EC number 3.6.5.2.