DDR48 — Candida albicans

Summary

C2_09220W_A (DDR48) on Candida albicans chromosome 2 encodes a stress-associated protein. The gene is associated with DNA damage response, homologous recombination, and response to MMS, as well as IMP anabolism, glutathione metabolism, sterol and ergosterol anabolism, and protein synthesis. DDR48 is associated with cellular responses to stress, oxidative stress, and starvation, and with filamentous growth in response to starvation and biotic stimulus, hyphal growth, morphogenesis, biofilm formation, flocculation, and cell death. The product localises to the hyphal cell wall and is cell-bound. DDR48 is also linked to the oxidative stress response trait.