RTA3 — Candida albicans

Summary

C2_06460W_A (RTA3) in Candida albicans chromosome 2 encodes a protein of the RTA1 family with ATPase-coupled intramembrane lipid carrier activity and ATP hydrolase activity. The gene is associated with regulation of phospholipid translocation, phospholipid translocation, lipid transport, lipid homeostasis, sterol metabolism, ergosterol anabolism, and the ER stress response. It is linked to biofilm formation, hyphal growth, mating, cell aggregation, cell growth, hypersensitivity, and the cellular response to xenobiotic stimulus. Additional associations include iron transport, carbohydrate metabolism, lipid metabolism, and oxidative stress response. The product localizes to the eisosome, fungal-type vacuole, cell tip, cell division site, Golgi complex, plasmalemma, membrane, and cytoplasm.