SOK2 — Aspergillus nidulans FGSC A4

Summary

ANIA_05836 (SOK2, also known as stuA) on chromosome 1 of Aspergillus nidulans FGSC A4 encodes a DNA-binding transcription factor belonging to the EFG1/Phd1/StuA and APSES-type helix-turn-helix protein families. The gene is associated with the regulation of asexual and sexual sporulation, including conidiophore development, cleistothecium development, fruiting body formation, and chlamydospore formation. It is also linked to terrein anabolism, cell differentiation, conidium germination, and regeneration. The encoded protein localises to the nucleus. Phenotypic associations include altered flocculation, biofilm formation, filamentous growth, pseudohyphal growth, mating type switching, adhesion, fermentative metabolism, and cell cycle progression. Related genes in other species link the family to turgor pressure and loss of pathogenicity.