uaY — Aspergillus nidulans FGSC A4

Summary

ANIA_06173 (uaY) on chromosome 1 of Aspergillus nidulans FGSC A4 encodes a Zn(II)2Cys6 transcription factor with DNA-binding transcription repressor activity specific to RNA polymerase II. The gene is associated with regulation of DNA-templated transcription, including both positive and negative regulation by RNA polymerase II, as well as response to ammonia, purine base breakdown, pigmentation, hypoxanthine transport, cellular response to oxidative stress, endocytosis, methylation, and gene conversion. The encoded product localises to the nucleus, nuclear membrane, cytoplasm, and cytosol. Studies of related genes in other species link the family to transcriptional regulation.