nudE — Aspergillus nidulans FGSC A4

Summary

ANIA_06125 (nudE) on Aspergillus nidulans chromosome 1 encodes a protein containing the NUDE domain and is associated with microtubule binding. The gene is linked to microtubule nucleation, microtubule dynamics, mitotic spindle orientation, vesicle transport along microtubules, and nuclear movement. It is also associated with cell division, chromosome localization and division, centrosome localization, and homeostasis. Associations with axon regeneration, neurogenesis, and brain development are noted, though these terms reflect the gene's annotation rather than established roles in this fungus. The encoded product localizes to the microtubule, kinetochore, and kinesin complex. Studies of related genes in other species link the NUDE family to germination rate, oxidative stress response, and phosphorus concentration, but these associations are not yet established for A. nidulans.