CBH1 — Aspergillus nidulans FGSC A4

Summary

ANIA_06156 (symbol CBH1, also known as AnCBH1 or CBP1) in Aspergillus nidulans FGSC A4 on chromosome 1 encodes a protein with a CenT-Element_Derived domain, an HTH_CenpB_DNA-bd_dom, a DDE_SF_endonuclease_dom, and a Homeobox-like_sf. The gene product is annotated for centromere binding, sequence-specific DNA binding, and chromatin adaptor molecular functions. It is associated with negative regulation of rDNA heterochromatin formation, carbon catabolite repression, donor selection, digestion, and the glucose effect. The protein localises to the condensed chromosome centric region, centromere complex, mating-type region heterochromatin, chromatin, and nucleus. Studies of related genes in other species link the family to HTH CENPB-type and DDE-1 domain-containing proteins.